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GOLPP in dogs: What every large-breed owner should know

by | May 28, 2025 | Latest Monthly Newsletters, Pet Care

Whilst GOLPP is a common condition in some larger-breed dogs, many owners simply haven’t heard of it. Here’s a gulp of information on GOLPP – what it is, the symptoms it causes, and what can be done to help affected pets.

What is GOLPP?

GOLPP (geriatric onset laryngeal paralysis polyneuropathy) is a condition where pets slowly develop progressive nerve dysfunction, which appears to particularly affect nerves of the larynx (the airway opening in the throat), oesophagus, and legs.

GOLPP is most common in elderly Labradors but is also seen in other older large-breed dogs such as Golden Retrievers, German Shepherds, and Greyhounds.

What symptoms does GOLPP cause?

Dogs with GOLPP develop paralysis of the cartilage folds in their throat that control air flow into the trachea (windpipe). This partially obstructs their airways, leading to symptoms such as:

  • Noisy breathing, mostly when panting
  • Breathing difficulties, particularly with excitement, exercise or hot/humid weather
  • Reduced exercise tolerance

Many patients will also experience weakness issues with their oesophagus, which leads to symptoms such as:

  • Regurgitation of food or water
  • Episodes of gagging or throat clearing

Patients will usually go on to develop progressive nerve dysfunction affecting their legs (which can be difficult to differentiate from arthritis), leading to symptoms such as:

  • An unsteady walk
  • Leg weakness
  • An abnormally wide stance
Can GOLPP be treated?

Unfortunately, GOLPP cannot be treated. However, pet’s quality of life can be significantly improved with treatment of the symptoms. Depending on the severity of their issues, pets may be treated with:

  • Specialist airway surgery to help hold open their larynx
  • Medications and a special diet to help reduce regurgitation
  • Physiotherapy to help maintain leg coordination and strength
  • Treatment of any concurrent arthritis to help support comfort and mobility

Dogs affected by GOLPP should be kept cool during summer and never exercised in hot or humid weather.

For more information on supporting older large breed doggos, consult our veterinary team – we’re clued up about canines!